| 9/16/2025 | Texas Rangers (5)
Houston Astros (6) | Houston Astros | 11 | | Money Line: | Houston Astros | Winner | | Spread: | No Pick | - | | Total: | No Pick | - |
|
| 9/16/2025 | Seattle Mariners (12)
Kansas City Royals (5) | Seattle Mariners | 17 | | Money Line: | Seattle Mariners | Winner | | Spread: | No Pick | - | | Total: | No Pick | - |
|
| 9/16/2025 | San Francisco Giants (5)
Arizona Diamondbacks (6) | Arizona Diamondbacks | 11 | | Money Line: | San Francisco Giants | Loser | | Spread: | No Pick | - | | Total: | No Pick | - |
|
| 9/16/2025 | San Diego Padres (3)
New York Mets (8) | New York Mets | 11 | | Money Line: | New York Mets | Winner | | Spread: | No Pick | - | | Total: | No Pick | - |
|
| 9/16/2025 | Toronto Blue Jays (6)
Tampa Bay Rays (5) | Toronto Blue Jays | 11 | | Money Line: | Toronto Blue Jays | Winner | | Spread: | No Pick | - | | Total: | No Pick | - |
|
